Fungal Immunology
Fungus is an eucharyotic organism that can be found in nature as a free living species in the decayed organic substance in ground, vegetations and body fluids. Fungus is independent of interaction with mammalian host to survive. Most of the fungus are harmless, but some of them can induce disease in human, called mycoses. The diseases vary from typical relatively surface infections to harmful systemic diseases particularly in immunodeficient hosts, depending on various factors including indigestible capsule (cryptotic), resistance against phagocytosis (histoplasm) and polymorphonuclear cell destruction (coccidiosis). Several fungus activate complement through alternative pathway, but the effect on their survival is not yet known. Antibodies can also be observed and are thought play role in immune response against fungus.